World Library  


Add to Book Shelf
Flag as Inappropriate
Email this Book

Toxicological Review of Trivalent Chromium

By Grevatt, Peter C., Ph. D.

Click here to view

Book Id: WPLBN0000080026
Format Type: PDF eBook
File Size: 0.4 MB
Reproduction Date: 2007
Full Text

Title: Toxicological Review of Trivalent Chromium  
Author: Grevatt, Peter C., Ph. D.
Volume:
Language: English
Subject: Ecology, Natural resource issues, Environemtal protection
Collections: Environmental Awareness Library Collection
Historic
Publication Date:
Publisher: United States Environmental Protection Agency

Description
Excerpt: This document and summary information on IRIS have received peer review both by EPA scientists and by independent scientists external to EPA. Subsequent to external review and incorporation of comments, this assessment has undergone an Agencywide review process whereby the IRIS Program Manager has achieved a consensus approval among the Office of Research and Development; Office of Air and Radiation; Office of Prevention, Pesticides, and Toxic Substances; Office of Solid Waste and Emergency Response; Office of Water; Office of Policy, Planning, and Evaluation; and the Regional Offices.

Table of Contents
CONTENTS—TOXICOLOGICAL REVIEW FOR TRIVALENT CHROMIUM (CAS No. 16065-83-1) FOREWORD ................................................................v AUTHORS, CONTRIBUTORS, AND REVIEWERS ................................ vi LISTOFABBREVIATIONS .................................................. vii 1. INTRODUCTION...........................................................1 2. CHEMICAL AND PHYSICAL INFORMATION RELEVANT TO ASSESSMENTS .....2 3. TOXICOKINETICS RELEVANT TO ASSESSMENTS ............................3 3.1. ABSORPTION FACTORS IN HUMANS AND EXPERIMENTAL ANIMALS . . 3 3.1.1. Oral .......................................................3 3.1.2. Inhalation ..................................................4 3.1.3. Distribution .................................................5 3.1.4. Metabolism .................................................7 3.1.5. The Essentiality of Chromium ..................................7 4. HAZARDIDENTIFICATION .................................................8 4.1. STUDIES IN HUMANS ..............................................8 4.1.1. Oral .......................................................8 4.1.2. Inhalation ..................................................8 4.2. PRECHRONIC AND CHRONIC STUDIES AND CANCER BIOASSAYS IN ANIMALS—ORAL AND INHALATION .............................12 4.2.1. Chronic Oral Studies.........................................12 4.2.2. Subchronic Oral Studies ......................................13 4.2.3. Chronic Inhalation Studies ....................................14 4.2.4. Subchronic Inhalation Studies .................................15 4.3. REPRODUCTIVE/DEVELOPMENTAL STUDIES—ORAL AND INHALATION ............................................................... 17 4.3.1. Oral Studies......................................................17 4.3.2. Inhalation Studies ...........................................18 4.4. OTHER STUDIES................................................19 4.4.1. Contact Dermatitis ..........................................19 4.4.2. Toxicant Interactions.........................................19 4.4.3. Genotoxicity ...............................................19 4.5. SYNTHESIS AND EVALUATION OF MAJOR NONCANCER EFFECTS AND MODE OF ACTION (IF KNOWN)—ORAL AND INHALATION ......... 20 4.5.1. Oral Studies................................................20 4.5.1.1. Human Studies ...................................... 20 4.5.1.2. Animal Studies ...................................... 20

 

Click To View

Additional Books


  • National Wetland Mitigation Banking Stud... (by )
  • Phosphorus Removal Efficiency Upgrading ... Volume Historical Review (by )
  • Deep Sea Sedimentation (by )
  • Grain Size Distribution of the Surface S... (by )
  • Remediation and Restoration of an Oil Co... (by )
  • Phosphorus Removal Efficiency Upgrading ... Volume Sampling Program (by )
  • A Model of Organic Chemical Fate in a Bi... (by )
  • Impact of Sault Ste. Marie East End Wast... (by )
  • Wetlands : Their Use and Regulation (by )
  • Aquatic and Wetland Plants of Southweste... (by )
  • Tudur - Urban Environment Tg April 2-3, ... (by )
  • Mercury in Surficial Sediments (by )
Scroll Left
Scroll Right

 



Copyright © World Library Foundation. All rights reserved. eBooks from World Library are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.